Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922994 | 0.88 | CA12 (0.37) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7068989 | 0.87 | AR (0.41) | — | |
| SCHEMBL6928605 | 0.83 | HPRT1 (0.31) | GRIN1 | |
| SCHEMBL6926886 | 0.80 | — | — | |
| SCHEMBL6929441 | 0.80 | — | — | |
| SCHEMBL6923314 | 0.78 | GRIN2D (0.42) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL6928590 | 0.78 | DAO (0.46) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7739895 | 0.78 | AKR1C3 (0.36) | GRIN1 | |
| SCHEMBL7742775 | 0.76 | CYP1A2 (0.40) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8340390 | 0.75 | GRIA1 (0.43) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596709-B1 | For treatment of Alzheimer's disease, schizophrenia, amyotrophic lateral sclerosis, and Huntington's chorea | LES LABORATOIRES SERVIER (FR) | 2003-07-22 | — | — | US | disclosed |
| US-6518258-B1 | 6-sulphamoyl -3-quinolyphosphonic acid compounds | LES LABORATOIRES SERVIER (FR) | 2003-02-11 | — | — | US | disclosed |
| US-6420386-B1 | SPINAL TRAUMATISM, EPILEPSY, CHRONIC NEURODEGENERATIVE DISEASES SUCH AS ALZHEIMER'S DISEASE, SCHIZOPHRENIA, LATERAL AMYOTROPHIC SCLEROSIS OR HUNTINGTON'S CHOREA. | LES LABORATORIES SERVIER (FR) | 2002-07-16 | — | — | US | disclosed |