Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922910 | 0.84 | HSD11B1 (0.40) | SLC6A4SLC6A3ALDH1A1MAPK1LMNA | |
| SCHEMBL5538596 | 0.78 | LMNA (0.40) | ALDH1A1LMNASMN1; SMN2L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL6926708 | 0.77 | LMNA (0.40) | ALDH1A1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL11025430 | 0.74 | SLC6A2 (0.47) | SLC6A4SLC6A3MAPK1SLC6A2KDM4E | |
| SCHEMBL3519999 | 0.73 | SLC6A3 (0.51) | SLC6A4SLC6A3POLBALDH1A1LMNA | |
| SCHEMBL3518308 | 0.73 | SLC6A3 (0.53) | SLC6A4SLC6A3EPHX2ALDH1A1MAPK1 | |
| SCHEMBL3516430 | 0.73 | SLC6A3 (0.53) | SLC6A4SLC6A3EPHX2ALDH1A1MAPK1 | |
| SCHEMBL3516426 | 0.73 | SLC6A3 (0.53) | SLC6A4SLC6A3EPHX2ALDH1A1MAPK1 | |
| SCHEMBL3518306 | 0.73 | SLC6A3 (0.53) | SLC6A4SLC6A3EPHX2ALDH1A1MAPK1 | |
| SCHEMBL3516428 | 0.73 | SLC6A3 (0.53) | SLC6A4SLC6A3EPHX2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |