SCHEMBL69236

SCHEMBL69236

O=C(O)/C=C/c1cccc(C(=O)O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 3/20 0.66
TTR P02766 5/20 0.64
UNG P13051 1/20 0.63
NPSR1 Q6W5P4 1/20 0.62
HDAC3 O15379 3/20 0.61
HDAC1 Q13547 3/20 0.61
HDAC4 P56524 2/20 0.61
HDAC7 Q8WUI4 2/20 0.61
HDAC2 Q92769 2/20 0.61
HDAC10 Q969S8 2/20 0.61
HDAC11 Q96DB2 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
HDAC9 Q9UKV0 2/20 0.61
HDAC5 Q9UQL6 2/20 0.61
TNKS O95271 1/20 0.61
HCAR2 Q8TDS4 1/20 0.61
TNKS2 Q9H2K2 1/20 0.61
FBP1 P09467 1/20 0.60
PKM P14618 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69237 1.00 P4HB (0.66) P4HBTTRUNGNPSR1HDAC3
SCHEMBL13860524 0.95 TTR (0.63) P4HBTTRUNGNPSR1HDAC3
SCHEMBL13860523 0.95 TTR (0.63) P4HBTTRUNGNPSR1HDAC3
SCHEMBL808972 0.88 TTR (0.79) P4HBTTRUNGFBP1HSD17B10
SCHEMBL808971 0.88 TTR (0.79) P4HBTTRUNGFBP1HSD17B10
SCHEMBL8899992 0.88 TTR (0.79) P4HBTTRUNGFBP1HSD17B10
SCHEMBL9075299 0.88 TTR (0.79) P4HBTTRUNGFBP1HSD17B10
SCHEMBL69146 0.86 NPSR1 (0.74) TTRNPSR1HDAC3HDAC1HDAC4
SCHEMBL271386 0.86 NPSR1 (0.74) TTRNPSR1HDAC3HDAC1HDAC4
SCHEMBL7496023 0.85 PKM (0.60) P4HBTTRNPSR1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007676-A1 HDAC INHIBITORS FOR USE WITH NK CELL BASED THERAPIES VIRACTA THERAPEUTICS INC (US) 2026-01-08 US claimed
US-20240390375-A1 METHODS AND COMPOSITIONS FOR TREATING VIRAL OR VIRALLY-INDUCED CONDITIONS Viracta Subsidiary, Inc. (US) 2024-11-28 US claimed
WO-2024192348-A2 METHODS OF TREATING HPV IN HIV-INFECTED PATIENTS OHIO STATE INNOVATION FOUNDATION (US) 2024-09-19 WO claimed
US-20220249477-A1 METHODS AND COMPOSITIONS FOR TREATING VIRAL OR VIRALLY-INDUCED CONDITIONS VIRACTA THERAPEUTICS, INC. (US) 2022-08-11 US claimed
US-20200368280-A1 EPIGENETIC MODIFIERS FOR USE IN CELLULAR IMMUNOTHERAPY Viracta Subsidiary, Inc. 2020-11-26 US claimed
CN-111836636-A Epigenetic modifiers for cellular immunotherapy 维拉克塔治疗公司 2020-10-27 CN claimed
US-20190290646-A1 HDAC INHIBITORS FOR USE WITH NK CELL BASED THERAPIES INFINITY SA LLC, AS PURCHASER AGENT 2019-09-26 US claimed
US-20130331313-A1 METHODS AND COMPOSITIONS FOR TREATING VIRAL OR VIRALLY-INDUCED CONDITIONS TRUSTEES OF BOSTON UNIVERSITY 2013-12-12 US claimed
US-20110245154-A1 Methods and Compositions for Treating Viral or Virally-Induced Conditions HEMAQUEST PHARMACEUTICALS, INC. (US) 2011-10-06 US claimed
EP-1746982-A2 HISTONE DEACETYLASES INHIBITORS AGAINST HYPERLIPIDAEMIAS, ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASES UNIVERSITA'DEGLI STUDI DI MILANO (IT) 2007-01-31 EP claimed
WO-2005105066-A2 HISTONE DEACETYLASES INHIBITORS AGAINST HYPERLIPIDAEMIAS, ATHEROSCLEROSIS, CARDIOVASCULAR DISEASES UNIVERSITA' DEGLI STUDI DI MILANO (IT) 2005-11-10 WO claimed
US-20050075282-A1 Materials and methods for inhibiting the development of epilepsy NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-04-07 US claimed
US-4654412-A UNSATURATED MONOMERS, FIBERS, FILMS, MOLDINGS CELANESE CORPORATION (US) 1987-03-31 US claimed
US-20260117185-A1 ENHANCEMENT OF FIBROBLAST PLASTICITY FOR TREATMENT OF DISC DEGENERATION SPINALCYTE, LLC (US) 2026-04-30 US disclosed
US-20260007676-A1 HDAC INHIBITORS FOR USE WITH NK CELL BASED THERAPIES VIRACTA THERAPEUTICS INC (US) 2026-01-08 US disclosed
US-20260000672-A1 HISTONE DEACETYLASE INHIBITORS FOR USE IN IMMUNOTHERAPY VIRACTA SUBSIDIARY INC (US) 2026-01-01 US disclosed
US-5052188-A Desiccant materials for use in gas fired cooling and dehumidification equipment GAS RESEARCH INSTITUTE (US) 1991-10-01 US disclosed
US-4654412-A UNSATURATED MONOMERS, FIBERS, FILMS, MOLDINGS CELANESE CORPORATION (US) 1987-03-31 US disclosed
US-4120825-A ZEOLITES UNION OIL COMPANY OF CALIFORNIA (US) 1978-10-17 US disclosed
US-4066628-A REACTING ORGANIC ISOCYANATE WITH AN EPOXIDE MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117185-A1 ENHANCEMENT OF FIBROBLAST PLASTICITY FOR TREATMENT OF DISC DEGENERATION HDAC3, HDAC4, GSK3B P4HB 1657/4885TTR 3239/4885UNG 2746/4885
US-20260007676-A1 HDAC INHIBITORS FOR USE WITH NK CELL BASED THERAPIES HDAC9, HDAC4, HDAC5 P4HB 664/4885TTR 4869/4885UNG 2061/4885
US-20260000672-A1 HISTONE DEACETYLASE INHIBITORS FOR USE IN IMMUNOTHERAPY HDAC7, HDAC8, HDAC9 P4HB 2555/4885TTR 1885/4885UNG 1467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.