Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593411 | 0.79 | GABRA1 (0.41) | AMY1AHSPA5HIF1ACYP2C9CYP2C19 | |
| SCHEMBL2290449 | 0.79 | ALDH1A1 (0.33) | AMY1AHSPA5HIF1ACYP2C9CYP2C19 | |
| SCHEMBL27201791 | 0.78 | ALDH1A1 (0.39) | SHBGHIF1AHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL30689827 | 0.78 | ALDH1A1 (0.39) | SHBGHIF1AHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL31719880 | 0.78 | SHBG (0.34) | SHBGHIF1ASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL6825431 | 0.77 | ALDH1A1 (0.37) | SHBGHIF1AHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL357123 | 0.76 | SHBG (0.39) | SHBGAMY1AHSPA5HIF1ACYP2C9 | |
| SCHEMBL30425753 | 0.76 | SHBG (0.39) | SHBGAMY1AHSPA5HIF1ACYP2C9 | |
| SCHEMBL12954538 | 0.75 | PDE4A (0.47) | SMN1; SMN2ALDH1A1ALOX15PDE4APDE4B | |
| SCHEMBL17429686 | 0.75 | KDM4E (0.40) | AMY1AHSPA5HIF1ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |