Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254947 | 0.72 | ABCG2 (0.90) | ABCG2MAPTNPC1MEN1KMT2A | |
| SCHEMBL4254944 | 0.72 | ABCG2 (0.90) | ABCG2MAPTNPC1MEN1KMT2A | |
| SCHEMBL22024170 | 0.71 | NPC1 (0.61) | LMNAMAPTNPC1MEN1KMT2A | |
| SCHEMBL7373223 | 0.71 | NPC1 (0.61) | LMNAMAPTNPC1MEN1KMT2A | |
| SCHEMBL7373222 | 0.71 | NPC1 (0.61) | LMNAMAPTNPC1MEN1KMT2A | |
| SCHEMBL21863298 | 0.69 | HTT (0.45) | KDM4ELTB4RNPC1MEN1KMT2A | |
| SCHEMBL977481 | 0.69 | MAPT (0.67) | ABCG2MAPTEGFRMMP1MMP2 | |
| SCHEMBL977479 | 0.69 | MAPT (0.67) | ABCG2MAPTEGFRMMP1MMP2 | |
| SCHEMBL14801940 | 0.68 | LMNA (0.57) | KDM4ELMNAMAPTNPC1TNFRSF1A | |
| SCHEMBL12427635 | 0.68 | HTT (0.50) | KDM4EMAPTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351553-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH (DE) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022258792-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2022-12-15 | — | — | WO | disclosed |
| EP-1180027-A4 | METHOD FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EVENTS ASSOCIATED WITH CORONARY INTERVENTION | SMITHKLINE BEECHAM CORP (US) | 2004-11-17 | — | — | EP | disclosed |
| EP-1180027-A1 | METHOD FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EVENTS ASSOCIATED WITH CORONARY INTERVENTION | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000045810-A1 | METHOD FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EVENTS ASSOCIATED WITH CORONARY INTERVENTION | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-10 | — | — | WO | disclosed |