Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20976791 | 0.81 | MYC (0.46) | HTTCA12CA1CA2CA9 | |
| SCHEMBL20976770 | 0.73 | ALDH1A1 (0.45) | CA12CA1CA2CA9CA7 | |
| SCHEMBL12427635 | 0.73 | HTT (0.50) | HTTCA12CA1CA2CA9 | |
| SCHEMBL148830 | 0.70 | G6PD (0.60) | HTTCA12CA1CA2CA9 | |
| SCHEMBL30852229 | 0.70 | G6PD (0.60) | HTTCA12CA1CA2CA9 | |
| SCHEMBL20976773 | 0.70 | WDR5 (0.50) | HTTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6923818 | 0.69 | KDM4E (0.50) | HTTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20976794 | 0.69 | MAPT (0.42) | HTTCA12CA1CA2CA9 | |
| SCHEMBL29365231 | 0.69 | HTT (0.78) | HTTCA12CA1CA2CA9 | |
| SCHEMBL3527 | 0.69 | HTT (0.78) | HTTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |