SCHEMBL14801940

SCHEMBL14801940

O=C(O)c1ccccc1N(O)C(=O)C=Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
TRPM8 Q7Z2W7 3/20 0.51
KDM4E B2RXH2 2/20 0.50
MAPT P10636 5/20 0.49
NPC1 O15118 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 2/20 0.47
HDAC3 O15379 2/20 0.47
HDAC4 P56524 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
PLIN1 O60240 2/20 0.47
RECQL P46063 2/20 0.47
PLIN5 Q00G26 2/20 0.47
ABHD5 Q8WTS1 2/20 0.47
TNKS O95271 1/20 0.47
HCAR2 Q8TDS4 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14802095 0.84 GUSB (0.54) LMNATRPM8KDM4EMAPTNPC1
SCHEMBL836333 0.81 TRPM8 (0.70) LMNATRPM8MAPTNPC1L3MBTL1
SCHEMBL836332 0.81 TRPM8 (0.70) LMNATRPM8MAPTNPC1L3MBTL1
SCHEMBL5436122 0.77 NPC1 (0.49) LMNATRPM8KDM4EMAPTNPC1
SCHEMBL5436123 0.77 NPC1 (0.49) LMNATRPM8KDM4EMAPTNPC1
SCHEMBL14802102 0.74 ALDH1A1 (0.41) LMNATRPM8KDM4EMAPTALDH1A1
SCHEMBL2441377 0.74 NPY2R (0.51) LMNATRPM8KDM4EMAPTNPC1
SCHEMBL7527743 0.72 LMNA (0.45) LMNATRPM8KDM4EMAPTALDH1A1
SCHEMBL25202121 0.72 MAPT (0.73) LMNAKDM4EMAPTNPC1ALDH1A1
SCHEMBL30383301 0.72 MAPT (0.73) LMNAKDM4EMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed