Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919302 | 0.84 | TSHR (0.43) | TSHRCYP19A1SMN1; SMN2NLRP3HTT | |
| SCHEMBL4304473 | 0.83 | TSHR (0.39) | TSHRCYP19A1RAB9AMAPTLMNA | |
| SCHEMBL4313108 | 0.77 | TSHR (0.35) | TSHRRAB9AMAPTLMNAKDM4E | |
| SCHEMBL28693817 | 0.74 | GSK3B (0.45) | TSHRMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL6682451 | 0.73 | KMT2A (0.47) | RAB9AMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL6923839 | 0.72 | MAPT (0.41) | TSHRCYP19A1RAB9AMAPTLMNA | |
| SCHEMBL28697186 | 0.70 | ALDH1A1 (0.42) | TSHRMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL7094207 | 0.69 | CYP19A1 (0.55) | CYP19A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL28362285 | 0.68 | L3MBTL1 (0.50) | TSHRCYP19A1RAB9AMAPTLMNA | |
| SCHEMBL6678954 | 0.67 | CAPN1 (0.38) | TSHRRAB9AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |