Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923835 | 0.84 | TSHR (0.39) | TSHRFDPSNLRP3SMN1; SMN2CYP19A1 | |
| SCHEMBL30595455 | 0.72 | FDPS (0.45) | TSHRFDPSNLRP3TDP1HDAC1 | |
| SCHEMBL4307811 | 0.71 | ADRB1 (0.44) | — | |
| SCHEMBL6679211 | 0.69 | PTPRA (0.46) | FDPSSMN1; SMN2 | |
| SCHEMBL7789025 | 0.69 | KMT2A (0.48) | POLBHTT | |
| SCHEMBL4304627 | 0.69 | HMOX1 (0.43) | SMN1; SMN2CYP19A1 | |
| SCHEMBL4310334 | 0.69 | PTGS2 (0.39) | CYP19A1 | |
| SCHEMBL13667412 | 0.69 | CYP1A2 (0.38) | TSHRTHRB | |
| SCHEMBL4308663 | 0.69 | ADRB1 (0.36) | — | |
| SCHEMBL4321687 | 0.69 | CYP1A2 (0.38) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |