Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935200 | 0.87 | SIGMAR1 (0.43) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL6932627 | 0.87 | SIGMAR1 (0.43) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL6932624 | 0.87 | SIGMAR1 (0.43) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL2750726 | 0.82 | OPRD1 (0.51) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL2751375 | 0.82 | OPRD1 (0.51) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL21831852 | 0.81 | DGKA (0.46) | OPRD1SIGMAR1 | |
| SCHEMBL6925678 | 0.80 | CYP1A2 (0.47) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL6928895 | 0.79 | OPRD1 (0.33) | OPRD1CYP1A2CYP3A4OPRM1 | |
| SCHEMBL6472695 | 0.79 | CYP1A2 (0.42) | OPRD1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL7623057 | 0.79 | CYP1A2 (0.37) | OPRD1CYP1A2CYP3A4CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514975-B1 | Tetrazoles as selective agonists for the delta opioid receptor | PFIZER INC | 2003-02-04 | — | — | US | disclosed |