Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919717 | 0.87 | P2RX7 (0.42) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6652027 | 0.78 | OPRD1 (0.50) | OPRD1USP2TP53CYP1A2CYP2C9 | |
| SCHEMBL6652014 | 0.78 | OPRD1 (0.50) | OPRD1USP2TP53CYP1A2CYP2C9 | |
| SCHEMBL6652019 | 0.78 | OPRD1 (0.50) | OPRD1USP2TP53CYP1A2CYP2C9 | |
| SCHEMBL6657412 | 0.78 | OPRD1 (0.47) | OPRD1USP2TP53CYP1A2CYP2C9 | |
| SCHEMBL6924540 | 0.78 | OPRD1 (0.47) | OPRD1USP2TP53CYP1A2CYP2C9 | |
| SCHEMBL6927106 | 0.75 | OPRD1 (0.41) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6654705 | 0.69 | OPRD1 (0.48) | OPRD1USP2OPRM1OPRK1 | |
| SCHEMBL6654701 | 0.69 | OPRD1 (0.48) | OPRD1USP2OPRM1OPRK1 | |
| SCHEMBL6654713 | 0.69 | OPRD1 (0.48) | OPRD1USP2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514975-B1 | Tetrazoles as selective agonists for the delta opioid receptor | PFIZER INC | 2003-02-04 | — | — | US | disclosed |