SCHEMBL83923

SCHEMBL83923

C=CCc1ccccc1C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
MAPT P10636 4/20 0.45
ALDH1A1 P00352 2/20 0.45
TSHR P16473 2/20 0.45
HSD17B10 Q99714 2/20 0.45
HPGD P15428 1/20 0.45
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
CYP3A4 P08684 2/20 0.43
METAP2 P50579 1/20 0.42
BCAT2 O15382 1/20 0.41
ICAM1 P05362 1/20 0.40
SELE P16581 1/20 0.40
VCAM1 P19320 1/20 0.40
JAK1 P23458 1/20 0.40
TYK2 P29597 1/20 0.40
JAK3 P52333 1/20 0.40
MEN1 O00255 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4442413 0.98 KDM4E (0.49) KDM4EMAPTALDH1A1TSHRHSD17B10
Benzamide SCHEMBL28198506 0.92 MAPT (0.52) KDM4EMAPTALDH1A1TSHRHSD17B10
Anthranilic Acid SCHEMBL28965730 0.87 ALDH1A1 (0.47) KDM4EMAPTALDH1A1TSHRHSD17B10
Phenethylamine SCHEMBL8056057 0.86 MAPT (0.47) KDM4EMAPTALDH1A1HPGDHDAC3
SCHEMBL9789603 0.86 BCAT2 (0.49) KDM4EMAPTALDH1A1TSHRHSD17B10
SCHEMBL89060 0.84 FOLH1 (0.55) KDM4EMAPTALDH1A1TSHRHPGD
SCHEMBL474921 0.84 GABRA1 (0.47) KDM4EMAPTALDH1A1TSHRHSD17B10
Benzene SCHEMBL27083018 0.84 FOLH1 (0.55) KDM4EMAPTALDH1A1TSHRHPGD
SCHEMBL12611132 0.84 GABRA1 (0.58) KDM4EMAPTALDH1A1TSHRHSD17B10
SCHEMBL7870129 0.84 GABRA1 (0.44) KDM4EMAPTALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023177842-A1 COPPER-CATALYZED AMIDATION OF POLYOLEFINS BASF CORPORATION (US) 2023-09-21 WO claimed
CN-114642210-A Suspending agent containing methoxy carbamate and cyazofamid and application thereof 山东统防生物科技有限公司 2022-06-21 CN claimed
CN-110511521-B Polyallylbenzamide-graphene hydrogel and preparation method thereof 吉林省七维生物科技有限公司 2021-12-14 CN claimed
CN-108473429-B ROR gamma modulators 领先制药控股公司 2021-09-10 CN claimed
US-10927283-B2 Friction-reducing compositions for use in drilling operations EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-23 US claimed
CN-106928142-B The 1,3- isoquinolin derovatives and preparation method thereof replaced containing arylthio 丽水学院 2019-10-25 CN claimed
US-20180179431-A1 Friction-Reducing Compositions for Use in Drilling Operations EXXONMOBIL CHEMICAL PATENTS INC. 2018-06-28 US claimed
US-20180179432-A1 Friction-Reducing Compositions for Use in Drilling Operations EXXONMOBIL CHEMICAL PATENTS INC. 2018-06-28 US claimed
CN-107459530-A A kind of 1,3 isoquinolin derovatives of novel silicon base substitution and preparation method thereof 丽水学院 2017-12-12 CN claimed
CN-106928142-A 1,3 isoquinolin derovatives containing arylthio substitution and preparation method thereof 丽水学院 2017-07-07 CN claimed
WO-2005070204-A1 PESTICIDE COMPOSITIONS AND METHODS FOR THEIR USE YAMASHITA THOMAS (US) 2005-08-04 WO claimed
US-20050158355-A1 pesticide and an assimilable carbon skeleton energy component such as corn steep liquor; reduces pesticide-induced phytotoxicity of a plant YAMASHITA THOMAS T (US) 2005-07-21 US claimed
EP-0875142-B1 Stable pesticide dispersions ROHM & HAAS (US) 2003-07-02 EP claimed
US-6210696-B1 Stable pesticide dispersions ROHM AND HAAS COMPANY 2001-04-03 US claimed
EP-0670677-B1 Potentiator of Bacillus pesticidal activity ABBOTT LAB (US) 2000-01-26 EP claimed
JP-2859963-B2 1999-02-24 JP claimed
EP-0875142-A2 Stable presticide dispersions ROHM AND HAAS COMPANY (US) 1998-11-04 EP claimed
EP-0670677-A1 POTENTIATOR OF $i(BACILLUS) PESTICIDAL ACTIVITY ABBOTT LABORATORIES (US) 1995-09-13 EP claimed
WO-1994009630-A1 POTENTIATOR OF BACILLUS PESTICIDAL ACTIVITY NOVO NORDISK ENTOTECH, INC. (US) 1994-05-11 WO claimed
EP-0097353-A2 Improved process for interferon production THE WELLCOME FOUNDATION LIMITED (GB) 1984-01-04 EP claimed