Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428847 | 0.89 | MAPK14 (0.52) | SLC2A1EGLN2PLAUEGFRPOLB | |
| SCHEMBL28255681 | 0.86 | SLC2A1 (0.63) | SLC2A1EGFRPTGS2HSD17B1ALDH1A1 | |
| SCHEMBL6668020 | 0.85 | GABRA1 (0.45) | NSD2EGLN2HSD17B1MAP4K4MINK1 | |
| SCHEMBL6644495 | 0.84 | SLC22A12 (0.56) | NSD2HSD17B1MAP4K4KDM1AALDH1A1 | |
| SCHEMBL6668052 | 0.83 | EGLN1 (0.51) | NSD2EGLN2HSD17B1MAP4K4MINK1 | |
| SCHEMBL7402540 | 0.82 | SLC2A1 (0.56) | SLC2A1EGFRPTGS2HSD17B1ALDH1A1 | |
| SCHEMBL6883774 | 0.82 | HSD17B1 (0.59) | SLC2A1EGFRPOLBPTGS2HSD17B1 | |
| SCHEMBL7401479 | 0.81 | CA1 (0.53) | EGLN2PLAUPOLBRXFP1NAMPT | |
| SCHEMBL13063631 | 0.81 | CA1 (0.53) | EGLN2PLAUPOLBRXFP1NAMPT | |
| SCHEMBL6925340 | 0.81 | MAP4K4 (0.45) | EGLN2PLAUEGFRPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007493-A1 | ARYL PIPERIDINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA | GLAXO GROUP LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |