Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCLC | P48506 | 1/20 | 0.53 |
| ▸ | GLUL | P15104 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967238 | 0.85 | GLUL (0.52) | GCLCGLUL | |
| SCHEMBL195643 | 0.85 | GLUL (0.52) | GCLCGLUL | |
| SCHEMBL1980143 | 0.85 | GLUL (0.52) | GCLCGLUL | |
| SCHEMBL23649439 | 0.83 | GLUL (0.50) | GCLCGLUL | |
| SCHEMBL28229605 | 0.83 | GLUL (0.50) | GCLCGLUL | |
| Norvaline SCHEMBL38405 | 0.83 | — | — | |
| Norvaline SCHEMBL38404 | 0.83 | — | — | |
| Norvaline SCHEMBL21114359 | 0.83 | SLC1A2 (0.64) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| Norvaline SCHEMBL840389 | 0.83 | SLC1A2 (0.64) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| Norvaline SCHEMBL17449755 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |