SCHEMBL195643

SCHEMBL195643

NC(CP(=O)(O)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GLUL P15104 1/20 0.52
FOLH1 Q04609 1/20 0.48
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
GCLC P48506 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1980143 1.00 GLUL (0.52) GLULFOLH1PTGS1SLC7A11GCLC
SCHEMBL8967238 1.00 GLUL (0.52) GLULFOLH1PTGS1SLC7A11GCLC
SCHEMBL28229605 0.97 GLUL (0.50) GLULFOLH1PTGS1SLC7A11GCLC
SCHEMBL23649439 0.97 GLUL (0.50) GLULFOLH1PTGS1SLC7A11GCLC
Norvaline SCHEMBL6924739 0.85 GCLC (0.53) GLULGCLC
SCHEMBL13892954 0.80 PTGS1 (0.48) GLULPTGS1SLC7A11GCLC
SCHEMBL19697646 0.80 PTGS1 (0.48) GLULPTGS1SLC7A11GCLC
SCHEMBL5054657 0.80 PTGS1 (0.48) GLULPTGS1SLC7A11GCLC
SCHEMBL28341260 0.79 GABBR2 (0.42) GLULFOLH1
SCHEMBL13997104 0.77 PTGS1 (0.44) GLULPTGS1SLC7A11GCLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120324436-B Medicine for treating T cell acute lymphoblastic leukemia and application thereof People's Hospital Affiliated to Ningbo University (CN) 2026-05-26 CN claimed
US-20260124188-A1 mGluR receptor antagonists for use in prevention andor treatment of bone marrow lesions (BML) andor osteoporosis, cartilage loss, osteosclerosis and osteitis in a mammal ORPHELION AB (SE) 2026-05-07 US claimed
EP-4583872-A1 MGLUR5 RECEPTOR ANTAGONISTS FOR USE IN PREVENTION AND/OR TREATMENT OF BONE MARROW LESIONS (BML) AND/OR OSTEOPOROSIS, CARTILAGE LOSS, OSTEOSCLEROSIS, OSTEITIS IN A MAMMAL ORPHELION AB (SE) 2025-07-16 EP claimed
EP-3966344-B1 KINASE SCREENING ASSAYS UNIV NEWCASTLE (GB) 2025-06-25 EP claimed
CN-115920039-B Method for preparing ansamitocin P-3 loaded photo-responsive thermosensitive liposome by microfluidic technology and application 常州大学 2025-05-06 CN claimed
WO-2025069991-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE 富士フイルム株式会社 2025-04-03 WO claimed
CN-119677779-A Combination therapy with anti-nucleolin 1 antibodies and antibody conjugates 儿童医学中心公司 2025-03-21 CN claimed
CN-119487077-A Mutant and mislocalized cell surface nucleolin 1 as diagnostic and therapeutic targets for human diseases 儿童医学中心公司 2025-02-18 CN claimed
WO-2025026449-A1 MODIFIED CELLS AND USES THEREOF ST PHI THERAPEUTICS CO., LTD. (CN) 2025-02-06 WO claimed
CN-118684620-A Betel nut alkaloid and preparation method and application thereof 暨南大学 2024-09-24 CN claimed
WO-2006081392-A1 N-HALOGENATED AMINO ACIDS AND N, N-DIHALOGENATED AMINO ACIDS IN COMBINATION WITH HYPOHALOUS ACIDS NOVABAY PHARMACEUTICALS, INC. (US) 2006-08-03 WO claimed
US-20030202994-A1 Excitatory amino acid inhibitors for treating sensitive skins SOCIETE L'OREAL S.A. (FR) 2003-10-30 US claimed
US-6506738-B1 Treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection. BRISTOL-MYERS SQUIBB COMPANY 2003-01-14 US claimed
EP-0795337-B1 A method of preparing biological implantation material SORIN BIOMEDICA CARDIO SPA (IT) 2002-12-04 EP claimed
US-6001581-A Cation-based bioassay using human metabotropic glutamate receptors SIBIA NEUROSCIENCES, INC. (US) 1999-12-14 US claimed
EP-0904777-A1 Use of an excitatory amino acids inhibitor in cosmetic or dermatological compositions for sensitive kin and composition obtained L'OREAL (FR) 1999-03-31 EP claimed
US-5873812-A REDUCING PROSTHETIC ORGAN AND TISSUE REJECTION; BINDING EXCESS ALDEHYDE FIXATIVE BY TREATMENT WITH AN AMINOCARBOXYLIC ACID IN ACIDIC MEDIUM SORIN BIOMEDICA CARDIO S.P.A. (IT) 1999-02-23 US claimed
EP-0795337-A2 A method of preparing biological implantation material SORIN BIOMEDICA CARDIO S.p.A. (IT) 1997-09-17 EP claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
WO-1992019717-A1 A HIGH-AFFINITY HUMAN GLUTAMATE/ASPARTATE UPTAKE SYSTEM BAYLOR COLLEGE OF MEDICINE (US) 1992-11-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124188-A1 mGluR receptor antagonists for use in prevention andor treatment of bone marrow lesions (BML) andor osteoporosis, cartilage loss, osteosclerosis and osteitis in a mammal GRM5, OPRL1, GRM1 GLUL 268/4885FOLH1 2718/4885PTGS1 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.