SCHEMBL8967238

SCHEMBL8967238

N[C@H](CP(=O)(O)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GLUL P15104 1/20 0.52
FOLH1 Q04609 1/20 0.48
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
GCLC P48506 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1980143 1.00 GLUL (0.52) GLULFOLH1PTGS1SLC7A11GCLC
SCHEMBL195643 1.00 GLUL (0.52) GLULFOLH1PTGS1SLC7A11GCLC
SCHEMBL28229605 0.97 GLUL (0.50) GLULFOLH1PTGS1SLC7A11GCLC
SCHEMBL23649439 0.97 GLUL (0.50) GLULFOLH1PTGS1SLC7A11GCLC
Norvaline SCHEMBL6924739 0.85 GCLC (0.53) GLULGCLC
SCHEMBL13892954 0.80 PTGS1 (0.48) GLULPTGS1SLC7A11GCLC
SCHEMBL19697646 0.80 PTGS1 (0.48) GLULPTGS1SLC7A11GCLC
SCHEMBL5054657 0.80 PTGS1 (0.48) GLULPTGS1SLC7A11GCLC
SCHEMBL28341260 0.79 GABBR2 (0.42) GLULFOLH1
SCHEMBL13997104 0.77 PTGS1 (0.44) GLULPTGS1SLC7A11GCLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583872-A1 MGLUR5 RECEPTOR ANTAGONISTS FOR USE IN PREVENTION AND/OR TREATMENT OF BONE MARROW LESIONS (BML) AND/OR OSTEOPOROSIS, CARTILAGE LOSS, OSTEOSCLEROSIS, OSTEITIS IN A MAMMAL ORPHELION AB (SE) 2025-07-16 EP claimed
WO-2024088712-A1 MGLUR5 RECEPTOR ANTAGONISTS FOR USE IN PREVENTION AND/OR TREATMENT OF BONE MARROW LESIONS (BML) AND/OR OSTEOPOROSIS, CARTILAGE LOSS, OSTEOSCLEROSIS, OSTEITIS IN A MAMMAL ORPHELION AB (SE) 2024-05-02 WO claimed
EP-3966344-A1 KINASE SCREENING ASSAYS University of Newcastle Upon Tyne (GB) 2022-03-16 EP claimed
CN-105524492-A Simple low-cost magnetic fine particle surface active group introduction method UNIV SICHUAN 2016-04-27 CN claimed
CN-102176818-A Antimicrobial gel formulations NOVABAY PHARMACEUTICALS INC 2011-09-07 CN claimed
EP-4583872-A1 MGLUR5 RECEPTOR ANTAGONISTS FOR USE IN PREVENTION AND/OR TREATMENT OF BONE MARROW LESIONS (BML) AND/OR OSTEOPOROSIS, CARTILAGE LOSS, OSTEOSCLEROSIS, OSTEITIS IN A MAMMAL ORPHELION AB (SE) 2025-07-16 EP disclosed
WO-2024088712-A1 MGLUR5 RECEPTOR ANTAGONISTS FOR USE IN PREVENTION AND/OR TREATMENT OF BONE MARROW LESIONS (BML) AND/OR OSTEOPOROSIS, CARTILAGE LOSS, OSTEOSCLEROSIS, OSTEITIS IN A MAMMAL ORPHELION AB (SE) 2024-05-02 WO disclosed
EP-4284343-A1 PARTICLES COMPRISING AMORPHOUS DIVALENT METAL CARBONATE Amorphical Ltd. (IL) 2023-12-06 EP disclosed
WO-2023164661-A1 ALTERATION OF NUTRIENT PREFERENCES VIA MODULATION OF NUTRIENT RECEPTORS IN THE GUT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2023-08-31 WO disclosed
EP-4117685-A1 AMORPHOUS CALCIUM CARBONATE FOR TREATMENT OF ACIDOSIS Amorphical Ltd. (IL) 2023-01-18 EP disclosed
WO-2022162667-A1 PARTICLES COMPRISING AMORPHOUS DIVALENT METAL CARBONATE AMORPHICAL LTD. (IL) 2022-08-04 WO disclosed
US-11326169-B2 Method of producing an aptamer and uses thereof CITY UNIVERSITY OF HONG KONG (HK) 2022-05-10 US disclosed
CN-109996453-A Compounds for modulating calcium sensitive receptor activity for modulating kokumi taste and pet foods containing same 马斯公司 2019-07-09 CN disclosed
EP-2632470-B1 PERSONAL CARE COMPOSITIONS COMPRISING A PYRITHIONE AND AN IRON CHELATOR PROCTER & GAMBLE (US) 2018-02-28 EP disclosed
CN-105524492-A Simple low-cost magnetic fine particle surface active group introduction method UNIV SICHUAN 2016-04-27 CN disclosed
CN-102176818-A Antimicrobial gel formulations NOVABAY PHARMACEUTICALS INC 2011-09-07 CN disclosed
US-20080317834-A1 Compounds and methods for modulating cerebral amyloid angiopathy NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2008-12-25 US disclosed
US-20070078082-A1 Methods and compositions to treat glycosaminoglycan-associated molecular interactions NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-04-05 US disclosed
CN-1144529-A Heterocyclic compounds, their preparation and use NOVO NORDISK AS (DK) 1997-03-05 CN disclosed
US-5523430-A Protein farnesyl transferase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1996-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080317834-A1 Compounds and methods for modulating cerebral amyloid angiopathy APP, PYGB, MAPT GLUL 1420/4885FOLH1 1947/4885PTGS1 620/4885
US-20070078082-A1 Methods and compositions to treat glycosaminoglycan-associated molecular interactions HPSE, CD44, CSGALNACT1 GLUL 1997/4885FOLH1 132/4885PTGS1 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.