Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924004 | 0.85 | CTSL (0.31) | CTSLCTSSCTSK | |
| SCHEMBL7380160 | 0.77 | CTSL (0.35) | AAK1CTSLCTSSCTSKCACNA1B | |
| SCHEMBL6921579 | 0.77 | CTSL (0.31) | CTSLCTSSCTSK | |
| SCHEMBL6924847 | 0.76 | F2 (0.49) | ALDH1A1 | |
| SCHEMBL6078328 | 0.76 | AAK1 (0.34) | AAK1CACNA1BSMN1; SMN2 | |
| SCHEMBL6078138 | 0.75 | AAK1 (0.33) | AAK1CACNA1B | |
| SCHEMBL6077903 | 0.75 | AAK1 (0.33) | AAK1CACNA1BSMN1; SMN2 | |
| SCHEMBL6925791 | 0.74 | F2 (0.40) | ALDH1A1 | |
| SCHEMBL6919944 | 0.73 | HTRA1 (0.42) | ALDH1A1 | |
| SCHEMBL6924571 | 0.73 | TP53 (0.34) | AAK1CACNA1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515011-B2 | Anticoagulants | MERCK & CO., INC. | 2003-02-04 | — | — | US | disclosed |
| US-20020119992-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119992-A1 | Thrombin inhibitors | SERPINC1, F2, TFPI | AAK1 3541/4885CTSL 199/4885CTSS 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.