SCHEMBL692494

SCHEMBL692494

[CH2]CC(O)N1CCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA3 P07451 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
CHRM2 P08172 3/20 0.39
CHRM4 P08173 3/20 0.39
CHRM5 P08912 3/20 0.39
CHRM1 P11229 3/20 0.39
CHRM3 P20309 3/20 0.39
PIK3CD O00329 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660983 0.82 LMNA (0.49) LMNACA12CA1CA2CA3
SCHEMBL2457545 0.80 LMNA (0.61) LMNACA12CA1CA2CA3
SCHEMBL5667905 0.78 LMNA (0.46) LMNACA12CA1CA2CA3
SCHEMBL7197798 0.77 LMNA (0.53) LMNACA12CA1CA2CA3
SCHEMBL8714172 0.77 PIK3CD (0.56) LMNACA12CA1CA2CA3
SCHEMBL2362411 0.77
Ethylene Glycol SCHEMBL10785744 0.76 LMNA (0.56) LMNACA12CA1CA2CA3
SCHEMBL6121745 0.74 LMNA (0.54) LMNACA12CA1CA2CA3
SCHEMBL22042594 0.74 LMNA (0.50) LMNACA12CA1CA2CA3
SCHEMBL8609237 0.74 LMNA (0.54) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103393607-A Capsule formulation of pirfenidone and pharmaceutically acceptable excipients INTERMUNE INC 2013-11-20 CN claimed
CN-101267810-A Capsule preparation of pirfenidone and pharmaceutically acceptable excipients INTERMUNE INC (US) 2008-09-17 CN claimed
US-20230364078-A1 METHOD OF PREPARING NANOPARTICLES COMPRISING POORLY WATER SOLUBLE DRUGS FOR TREATING HEPATITIS EVEX Technology, Inc. 2023-11-16 US disclosed
EP-3458049-A1 METHODS OF TREATING SEPSIS WITH SYNAPTIC VESICLE 2A AND/OR 2B BINDING CHEMICAL ENTITIES Institut Pasteur (FR) 2019-03-27 EP disclosed
WO-2017198862-A1 METHODS OF TREATING SEPSIS WITH SYNAPTIC VESICLE 2A AND/OR 2B BINDING CHEMICAL ENTITIES INSTITUT PASTEUR (FR) 2017-11-23 WO disclosed
EP-2672952-B1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2016-06-15 EP disclosed
EP-2579838-B1 HAIR STYLING COMPOSITION UNILEVER PLC NO 41424 (GB) 2015-01-07 EP disclosed
EP-2768470-A2 HAIR STYLING COMPOSITION Unilever PLC, a company registered in England and Wales under company no. 41424 (GB) 2014-08-27 EP disclosed
US-20130142749-A1 HAIR STYLING COMPOSITION CONOPCO, INC., D/B/A UNILEVER 2013-06-06 US disclosed
WO-2013056888-A2 COMPOSITION UNILEVER PLC (GB) 2013-04-25 WO disclosed
EP-2421499-B1 Hair styling method UNILEVER PLC (GB) 2013-03-06 EP disclosed
EP-1438003-A1 COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2004-07-21 EP disclosed
EP-0818190-B1 Hair styling composition UNILEVER PLC (GB) 2003-10-29 EP disclosed
WO-2003035017-A1 COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2003-05-01 WO disclosed
EP-1269974-A1 Hair styling compositions UNILEVER PLC (GB) 2003-01-02 EP disclosed
US-6335000-B1 CROSS-LINKED DIMETHICONOL, POLYQUATERNIUM 16, AND VINYLCAPROLACTAM/VINYLPYRROLIDONE/VINYLIMIDAZOLIUM COPOLYMERS UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-01 US disclosed
US-20010029242-A1 Aqueous hair styling compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-10-11 US disclosed
US-6290932-B2 Comprising volatile silicone selected from a cyclic or trimethylsilanol endcapped polydimethylsiloxane, or low molecular weight compounds of these, hair styling polymer, surfactant, water and aerosol propellant; hair hold strength UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-09-18 US disclosed
US-20010009659-A1 AQUEOUS HAIR STYLING AIDS UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-07-26 US disclosed
EP-0818190-A2 Hair styling composition UNILEVER PLC (GB) 1998-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230364078-A1 METHOD OF PREPARING NANOPARTICLES COMPRISING POORLY WATER SOLUBLE DRUGS FOR TREATING HEPATITIS SLC10A1, CYP7A1, ABCB11 LMNA 3097/4885CA12 808/4885CA1 1866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.