Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PER2 | O15055 | 4/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011538 | 0.80 | PIK3CD (0.64) | PIK3CDTSHRPER2RCE1CYP2C19 | |
| SCHEMBL10664050 | 0.80 | PIK3CD (0.64) | PIK3CDTSHRPER2RCE1CYP2C19 | |
| SCHEMBL11121999 | 0.80 | PIK3CD (0.55) | PIK3CDTSHRPER2RCE1LMNA | |
| SCHEMBL10823329 | 0.79 | PIK3CD (0.69) | PIK3CDTSHRPER2RCE1LMNA | |
| SCHEMBL4660983 | 0.79 | LMNA (0.49) | PIK3CDTSHRPER2RCE1LMNA | |
| SCHEMBL692494 | 0.77 | LMNA (0.47) | PIK3CDTSHRPER2RCE1LMNA | |
| SCHEMBL2457545 | 0.77 | LMNA (0.61) | PIK3CDTSHRPER2LMNACA12 | |
| SCHEMBL2794323 | 0.77 | PIK3CD (0.71) | PIK3CDTSHRPER2RCE1LMNA | |
| SCHEMBL5667905 | 0.76 | LMNA (0.46) | PIK3CDTSHRPER2RCE1LMNA | |
| SCHEMBL1758375 | 0.76 | PIK3CD (0.58) | PIK3CDTSHRPER2RCE1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743842-A4 | DRUG-CONTAINING ADHESIVE COMPOSITE TRANSDERMAL DELIVERY DEVICE | THERATECH INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0743842-A1 | DRUG-CONTAINING ADHESIVE COMPOSITE TRANSDERMAL DELIVERY DEVICE | THERATECH, INC. (US) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995024172-A1 | DRUG-CONTAINING ADHESIVE COMPOSITE TRANSDERMAL DELIVERY DEVICE | THERATECH, INC. (US) | 1995-09-14 | — | — | WO | disclosed |