Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458517 | 1.00 | L3MBTL1 (0.52) | L3MBTL1SLC6A2SLC6A4POLBPARP1 | |
| SCHEMBL6457801 | 1.00 | L3MBTL1 (0.52) | L3MBTL1SLC6A2SLC6A4POLBPARP1 | |
| SCHEMBL6923366 | 0.83 | SLC6A4 (0.47) | SLC6A2SLC6A4PARP1SLC6A3 | |
| SCHEMBL6457544 | 0.83 | SLC6A4 (0.47) | SLC6A2SLC6A4PARP1SLC6A3 | |
| SCHEMBL516555 | 0.83 | L3MBTL1 (0.53) | L3MBTL1SLC6A2SLC6A4POLBPARP1 | |
| SCHEMBL517632 | 0.80 | ALOX5 (0.41) | SLC6A2SLC6A4SLC6A3OPRK1 | |
| Hydrochloric Acid SCHEMBL8616468 | 0.78 | SLC6A2 (0.62) | SLC6A2SLC6A4POLBSLC6A3OPRM1 | |
| SCHEMBL30816983 | 0.77 | L3MBTL1 (0.50) | L3MBTL1SLC6A2SLC6A4POLBPARP1 | |
| SCHEMBL15640766 | 0.73 | CYP17A1 (0.41) | POLBOPRM1 | |
| SCHEMBL5521100 | 0.73 | ALOX5 (0.42) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | claimed |