Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457544 | 1.00 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL6458517 | 0.83 | L3MBTL1 (0.52) | SLC6A4SLC6A3SLC6A2PARP1 | |
| SCHEMBL6457801 | 0.83 | L3MBTL1 (0.52) | SLC6A4SLC6A3SLC6A2PARP1 | |
| SCHEMBL6925029 | 0.83 | L3MBTL1 (0.52) | SLC6A4SLC6A3SLC6A2PARP1 | |
| SCHEMBL5521100 | 0.83 | ALOX5 (0.42) | SLC6A4SLC6A3SLC6A2LMNAHRH3 | |
| SCHEMBL6922904 | 0.82 | HSD11B1 (0.39) | SLC6A3SLC6A2ALDH1A1 | |
| SCHEMBL517632 | 0.81 | ALOX5 (0.41) | SLC6A4SLC6A3SLC6A2LMNAALOX5 | |
| SCHEMBL6460103 | 0.77 | TSHR (0.41) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL639268 | 0.76 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL2112323 | 0.72 | LMNA (0.68) | SLC6A4SLC6A3LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |