Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646010 | 0.85 | MAPT (0.42) | THRBKCNK3KCNK9KDM4ERAB9A | |
| SCHEMBL6649426 | 0.83 | THRB (0.44) | THRBKCNK3KCNK9NAMPTLMNA | |
| SCHEMBL6645481 | 0.80 | DGAT1 (0.40) | THRBKCNK3KCNK9LMNAKDM4E | |
| SCHEMBL6645791 | 0.80 | THRB (0.52) | THRBKCNK3KCNK9LMNARAB9A | |
| SCHEMBL6925222 | 0.77 | KCNK3 (0.37) | HTR2CTHRBKCNK3KCNK9KDM4E | |
| SCHEMBL6645584 | 0.73 | HCRTR2 (0.45) | HTR2CTHRBLMNAKDM4EUSP2 | |
| SCHEMBL6649330 | 0.72 | THRB (0.37) | THRBKCNK3KCNK9LMNAPOLB | |
| SCHEMBL6829032 | 0.72 | KMT2A (0.40) | THRBNAMPTLMNAKDM4ERAB9A | |
| SCHEMBL6925225 | 0.71 | KCNK3 (0.37) | HTR2CKCNK3KCNK9LMNAKDM4E | |
| SCHEMBL6645200 | 0.69 | HCRTR2 (0.40) | HTR2CTHRBKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |