Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831063 | 0.83 | RAB9A (0.45) | KMT2ARAB9ALMNATHRBNAMPT | |
| SCHEMBL6920000 | 0.82 | MGLL (0.41) | KMT2ARAB9ALMNATHRBNAMPT | |
| SCHEMBL6644390 | 0.76 | IDO1 (0.47) | KMT2ARAB9ALMNATHRBIDO1 | |
| SCHEMBL6829031 | 0.72 | THRB (0.41) | KMT2ALMNATHRBIDO1ALDH1A1 | |
| SCHEMBL6925229 | 0.72 | HTR2C (0.39) | RAB9ALMNATHRBNAMPTIDO1 | |
| SCHEMBL6923840 | 0.70 | MGLL (0.59) | KMT2ARAB9ATHRB | |
| SCHEMBL15189983 | 0.70 | NPC1 (0.46) | KMT2ARAB9ALMNAKDM4EMEN1 | |
| SCHEMBL15190034 | 0.69 | NAMPT (0.50) | RAB9ALMNANAMPTKDM4EALDH1A1 | |
| SCHEMBL15189988 | 0.69 | RAB9A (0.46) | KMT2ARAB9ALMNATHRBKDM4E | |
| SCHEMBL28230841 | 0.68 | TDP1 (0.43) | KMT2ALMNATHRBNAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |