Naphthalene

Naphthalene

SCHEMBL6925512

O=C1C=CC(=O)O1.c1ccc2ccccc2c1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.47
ALOX12 P18054 1/20 0.47
ALOX15 P16050 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TYMS P04818 2/20 0.39
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2B Q13224 2/20 0.39
GRIN2C Q14957 2/20 0.39
GRIN3A Q8TCU5 2/20 0.39
CA12 O43570 2/20 0.37
MCL1 Q07820 2/20 0.37
CA9 Q16790 2/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL9759855 0.89 GRIN2D (0.46) CYP2A6ALOX12ALOX15TDP1ALDH1A1
Maleic Anhydride SCHEMBL5638360 0.81 ALOX15 (0.39) ALOX15TDP1ALDH1A1CYP2C9HPGD
Maleic Anhydride SCHEMBL1761076 0.80 ALDH1A1 (0.37) ALOX15TDP1ALDH1A1CYP2C9HPGD
SCHEMBL10426127 0.80 ALDH1A1 (0.37) ALOX15TDP1ALDH1A1CYP2C9HPGD
Maleic Anhydride SCHEMBL10482026 0.80 ALDH1A1 (0.37) ALOX15TDP1ALDH1A1CYP2C9HPGD
Maleic Anhydride SCHEMBL1332547 0.80
Maleic Anhydride SCHEMBL1332543 0.80
Maleic Anhydride SCHEMBL191 0.80
Maleic Anhydride SCHEMBL1332137 0.80
Maleic Anhydride SCHEMBL10482080 0.80 ALDH1A1 (0.37) ALOX15TDP1ALDH1A1CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1204718-A4 MITIGATION OF FOULING BY THERMALLY CRACKED OILS EXXONMOBIL RES & ENG CO (US) 2003-09-24 EP disclosed
EP-1204718-A1 MITIGATION OF FOULING BY THERMALLY CRACKED OILS ExxonMobil Research and Engineering Company (US) 2002-05-15 EP disclosed
WO-2000077121-A1 MITIGATION OF FOULING BY THERMALLY CRACKED OILS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2000-12-21 WO disclosed