Anthracene

Anthracene

SCHEMBL9759855

O=C1C=CC(=O)O1.c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
PDE3B Q13370 1/20 0.41
PDE3A Q14432 1/20 0.41
HSP90AA1 P07900 1/20 0.39
GSTP1 P09211 1/20 0.38
ALOX15 P16050 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP3A4 P08684 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
HBB P68871 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL6925512 0.89 CYP2A6 (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Phenanthrene SCHEMBL27901311 0.80 ALDH1A1 (0.57) ALOX15TDP1ALDH1A1HSD17B10HIF1A
Maleic Anhydride SCHEMBL5638360 0.76 ALOX15 (0.39) HSP90AA1ALOX15TDP1ALDH1A1HSD17B10
Maleic Anhydride SCHEMBL1761076 0.76 ALDH1A1 (0.37) HSP90AA1ALOX15TDP1ALDH1A1HSD17B10
Maleic Anhydride SCHEMBL10482080 0.76 ALDH1A1 (0.37) HSP90AA1ALOX15TDP1ALDH1A1HSD17B10
Maleic Anhydride SCHEMBL1332543 0.76
Maleic Anhydride SCHEMBL10482026 0.76 ALDH1A1 (0.37) HSP90AA1ALOX15TDP1ALDH1A1HSD17B10
Maleic Anhydride SCHEMBL1332137 0.76
Maleic Anhydride SCHEMBL1332547 0.76
Maleic Anhydride SCHEMBL191 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10640466-B2 Anthracene based compounds and their uses UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION (GB) 2020-05-05 US disclosed
US-20180118685-A1 ANTHRACENE BASED COMPOUNDS AND THEIR USES UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION (GB) 2018-05-03 US disclosed
EP-3294730-A1 ANTHRACENE BASED COMPOUNDS AND THEIR USES University of Hertfordshire Higher Education Corporation (GB) 2018-03-21 EP disclosed
WO-2016181120-A1 ANTHRACENE BASED COMPOUNDS AND THEIR USES UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION (GB) 2016-11-17 WO disclosed
US-5025222-A System and method for monitoring substances and reactions PHASE DYNAMICS, INC. (US) 1991-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118685-A1 ANTHRACENE BASED COMPOUNDS AND THEIR USES CYP2D6, CYP3A43, ACMSD GRIN2D 3356/4885GRIN3B 3059/4885GRIN1 4255/4885
US-10640466-B2 Anthracene based compounds and their uses CYP2D6, CYP3A43, ACMSD GRIN2D 3356/4885GRIN3B 3059/4885GRIN1 4255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.