Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 8/20 | 0.48 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569346 | 0.85 | CCR2 (0.42) | PLA2G10CCR2MCL1MEN1MAPT | |
| SCHEMBL29475847 | 0.76 | PLA2G10 (0.48) | PLA2G10CCR2F10MCL1SLC9A1 | |
| SCHEMBL29374637 | 0.75 | PLA2G10 (0.40) | PLA2G10CCR2F10 | |
| SCHEMBL29475799 | 0.75 | CNR2 (0.44) | PLA2G10CCR2F10MCL1SLC9A1 | |
| SCHEMBL27695396 | 0.74 | CCR2 (0.41) | PLA2G10CCR2F10MCL1SLC9A1 | |
| SCHEMBL1573798 | 0.71 | PLA2G10 (0.78) | PLA2G10CCR2F10 | |
| SCHEMBL27580987 | 0.71 | PLA2G10 (0.46) | PLA2G10CCR2F10MCL1SLC9A1 | |
| SCHEMBL30044340 | 0.70 | CCR2 (0.58) | PLA2G10CCR2F10MCL1MEN1 | |
| SCHEMBL13738783 | 0.70 | CCR2 (0.58) | PLA2G10CCR2F10MCL1MEN1 | |
| SCHEMBL28109529 | 0.70 | PLA2G10 (0.64) | PLA2G10CCR2F10MCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469833-A2 | METHOD FOR MAKING HOMOGENEOUS SPRAY-DRIED SOLID AMORPHOUS DRUG DISPERSIONS UTILIZING MODIFIED SPRAY-DRYING APPARATUS | Pfizer Products Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1469830-A2 | METHOD FOR MAKING HOMOGENEOUS SPRAY-DRIED SOLID AMORPHOUS DRUG DISPERSIONS USING PRESSURE NOZZLES | Pfizer Products Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063821-A2 | METHOD FOR MAKING HOMOGENEOUS SPRAY-DRIED SOLID AMORPHOUS DRUG DISPERSIONS USING PRESSURE NOZZLES | PFIZER PRODUCTS INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003063822-A2 | METHOD FOR MAKING HOMOGENEOUS SPRAY-DRIED SOLID AMORPHOUS DRUG DISPERSIONS UTILIZING MODIFIED SPRAY-DRYING APPARATUS | PFIZER PRODUCTS INC. (US) | 2003-08-07 | — | — | WO | disclosed |