Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925634 | 0.85 | PLA2G10 (0.48) | CCR2MCL1MEN1MAPTKMT2A | |
| SCHEMBL13301226 | 0.70 | ALDH1A1 (0.50) | CCR2MCL1MEN1KMT2APOLB | |
| SCHEMBL5823619 | 0.64 | MCL1 (0.62) | CCR2MCL1POLBSLC9A1DAO | |
| SCHEMBL9568631 | 0.63 | DHFR (0.43) | MEN1MAPTKMT2APOLBKDM4E | |
| SCHEMBL11695585 | 0.62 | TP53 (0.40) | MEN1MAPTKMT2APOLBKDM4E | |
| SCHEMBL5806538 | 0.62 | MCL1 (0.58) | CCR2MCL1MAPTPOLBSLC9A1 | |
| SCHEMBL6701629 | 0.62 | MCL1 (0.50) | CCR2MCL1MEN1MAPTKMT2A | |
| SCHEMBL11687678 | 0.62 | KMT2A (0.49) | MEN1MAPTKMT2AKDM4ERECQL | |
| SCHEMBL27926662 | 0.62 | CCR2 (0.73) | CCR2MEN1KMT2AL3MBTL1PLA2G10 | |
| SCHEMBL30067600 | 0.61 | CCR2 (0.69) | CCR2MCL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404300-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | Pfizer Products Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000235-A9 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | PFIZER PROD INC (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003000235-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |