Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923759 | 0.95 | POLB (0.57) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL3069679 | 0.90 | ALDH1A1 (0.54) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL3075154 | 0.89 | PKM (0.59) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL6827778 | 0.88 | ITGA1 (0.52) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6923994 | 0.87 | PKM (0.53) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL6925435 | 0.86 | ALDH1A1 (0.55) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL6827768 | 0.85 | ALDH1A1 (0.57) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL6926084 | 0.85 | POLB (0.56) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL6827973 | 0.84 | PKM (0.61) | POLBALDH1A1LMNAPKMRAB9A | |
| SCHEMBL3071479 | 0.83 | ALDH1A1 (0.52) | POLBALDH1A1LMNAPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |