SCHEMBL6926334

SCHEMBL6926334

O=C(/C=C/c1ccccc1)OCOC(=O)Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.67
AKR1B10 O60218 7/20 0.63
AKR1B1 P15121 7/20 0.63
CA12 O43570 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
CA5B Q9Y2D0 1/20 0.57
MAOB P27338 1/20 0.54
ALDH1A1 P00352 1/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PAM P19021 1/20 0.51
APP P05067 1/20 0.50
TTR P02766 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6926335 1.00 LMNA (0.67) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL9855968 0.88 LMNA (0.71) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL9855964 0.88 LMNA (0.71) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL31344422 0.84 LMNA (0.61) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL6924534 0.82 AKR1B10 (0.65) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL6924531 0.82 AKR1B10 (0.65) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL6746067 0.81 LMNA (0.61) LMNAAKR1B10AKR1B1CA12CA4
SCHEMBL6746068 0.81 LMNA (0.61) LMNAAKR1B10AKR1B1CA12CA4
Benzyl Cinnamate SCHEMBL43213 0.80 LMNA (1.00) LMNAAKR1B10AKR1B1CA12CA4
Benzyl Cinnamate SCHEMBL43212 0.80 LMNA (1.00) LMNAAKR1B10AKR1B1CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973388-A4 UNSATURATED OXYALKYLENE ESTERS AND USES THEREOF BEACON LAB INC (US) 2003-03-19 EP claimed
EP-0973388-A1 UNSATURATED OXYALKYLENE ESTERS AND USES THEREOF Beacon Laboratories, Inc. (US) 2000-01-26 EP claimed
US-5939455-A Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives BEACON LABORATORIES, INC. (US) 1999-08-17 US claimed
WO-1998040078-A1 THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES BEACON LABORATORIES, INC. (US) 1998-09-17 WO claimed
WO-1998039965-A1 UNSATURATED OXYALKYLENE ESTERS AND USES THEREOF BEACON LABORATORIES, INC. (US) 1998-09-17 WO claimed
US-6599937-B1 For modulating gene expression in a hematopoietic cell BEACON LABORATORIES, INC. 2003-07-29 US disclosed
EP-0973388-A4 UNSATURATED OXYALKYLENE ESTERS AND USES THEREOF BEACON LAB INC (US) 2003-03-19 EP disclosed
US-6124495-A TREATING, PREVENTING OR AMELIORATING CANCER OR OTHER PROLIFERATIVE DISORDER; INCREASING HEMOGLOBIN CONTENT IN BLOOD; MODULATING AN IMMUNE RESPONSE; AMELIORATING THE EFFECTS OF A CYTOTOXIC AGENT; TREATING GASTROINTESTINAL DISORDERS BEACON LABORATORIES, INC. (US) 2000-09-26 US disclosed
EP-0973388-A1 UNSATURATED OXYALKYLENE ESTERS AND USES THEREOF Beacon Laboratories, Inc. (US) 2000-01-26 EP disclosed
US-5939455-A Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives BEACON LABORATORIES, INC. (US) 1999-08-17 US disclosed
WO-1998040078-A1 THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES BEACON LABORATORIES, INC. (US) 1998-09-17 WO disclosed
WO-1998039965-A1 UNSATURATED OXYALKYLENE ESTERS AND USES THEREOF BEACON LABORATORIES, INC. (US) 1998-09-17 WO disclosed