SCHEMBL6926451

SCHEMBL6926451

Cc1c[nH]c(=O)n(CCC(=O)O)c1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.52
KDM4E B2RXH2 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 2/20 0.48
HSD17B10 Q99714 2/20 0.48
APEX1 P27695 2/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 1/20 0.47
KMO O15229 4/20 0.46
MAPT P10636 1/20 0.44
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
PKM P14618 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153695 0.83 SLC9A1 (0.63) SLC9A1KDM4EAPEX1GRIN2DGRIN3B
SCHEMBL6928567 0.83 SLC9A1 (0.49) SLC9A1KDM4EPOLBALDH1A1
SCHEMBL15110502 0.80 SLC9A1 (0.51) SLC9A1POLBHPGDPDE4APDE4B
SCHEMBL16569628 0.80 APEX1 (0.47) KDM4EL3MBTL1POLBHSD17B10APEX1
SCHEMBL7643597 0.76 SLC9A1 (0.63) SLC9A1KDM4EALDH1A1HPGDGRIN2D
SCHEMBL16581427 0.76 ADORA2A (0.48) SLC9A1L3MBTL1POLBHPGDPDE4A
SCHEMBL3792986 0.75 SLC9A1 (0.47) SLC9A1PDE4APDE4BPDE4CPDE4D
SCHEMBL8876920 0.74 SLC9A1 (0.53) SLC9A1KDM4EPOLBALDH1A1PDE4A
SCHEMBL5586325 0.74 SLC9A1 (0.50) SLC9A1GRIN2DGRIN3BGRIA1GRIA2
SCHEMBL1058810 0.73 SLC9A1 (0.55) SLC9A1KDM4EGRIN2DGRIN3BGRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0960121-A4 PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY BUCHARDT DORTE (DK) 2003-05-28 EP disclosed
EP-0960121-A1 PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY BUCHARDT, Dorte (DK) 1999-12-01 EP disclosed
WO-1998003542-A1 PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY BUCHARDT, DORTE (DK) 1998-01-29 WO disclosed
EP-0586618-A1 THE USE OF NUCLEIC ACID ANALOGUES IN DIAGNOSTICS AND ANALYTICAL PROCEDURES. BUCHARDT OLE (DK) 1994-03-16 EP disclosed