Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110502 | 0.89 | SLC9A1 (0.51) | SLC9A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL16581427 | 0.84 | ADORA2A (0.48) | SLC9A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL7833004 | 0.81 | ADRA1D (0.43) | ADRA1AADRA1BADRA1DCYP3A4CYP2C9 | |
| SCHEMBL8876920 | 0.76 | SLC9A1 (0.53) | SLC9A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL7822379 | 0.76 | ADRA1A (0.50) | ADRA1AADRA1BADRA1DCYP3A4CYP2C9 | |
| SCHEMBL30555617 | 0.75 | SLC9A1 (0.46) | SLC9A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL6926451 | 0.75 | SLC9A1 (0.52) | SLC9A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1058810 | 0.74 | SLC9A1 (0.55) | SLC9A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL7643597 | 0.74 | SLC9A1 (0.63) | SLC9A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL11507992 | 0.72 | LMNA (0.46) | CYP3A4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557182-B2 | Site selectively tagged and templated molecularly imprinted polymers for sensor applications | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2013-10-15 | — | — | US | disclosed |
| US-8377717-B2 | Site selectively tagged and templated molecularly imprinted polymers for sensor applications | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2013-02-19 | — | — | US | disclosed |
| US-20100233828-A1 | Site Selectively Tagged and Templated Molecularly Imprinted Polymers for Sensor Applications | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE (US) | 2010-09-16 | — | — | US | disclosed |
| EP-1699832-A2 | SITE SELECTIVELY TAGGED AND TEMPLATED MOLECULARLY IMPRINTED POLYMERS FOR SENSOR APPLICATIONS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-0949250-B1 | Process for manufacturing alpha1L-adrenoceptor antagonists | HOFFMANN LA ROCHE (CH) | 2006-05-03 | — | — | EP | disclosed |
| US-20050227258-A1 | Site selectively tagged and templated molecularly imprinted polymers for sensor applications | NATIONAL SCIENCE FOUNDATION | 2005-10-13 | — | — | US | disclosed |
| WO-2005056613-A2 | SITE SELECTIVELY TAGGED AND TEMPLATED MOLECULARLY IMPRINTED POLYMERS FOR SENSOR APPLICATIONS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2005-06-23 | — | — | WO | disclosed |
| EP-0748800-B1 | Pyrimidinedione, pyrimidinetrione, triazinedione derivatives as alpha-1-adrenergic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2001-05-09 | — | — | EP | disclosed |
| US-5859014-A | USEFUL IN TREATMENT OF DISEASES INVOLVING DIRECTLY OR INDIRECTLY AN OBSTRUCTION OF THE LOWER URINARY TRACT, SUCH ASBENIGN PROSTATE HYPERPLASIA | SYNTEX (U.S.A.) INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0748800-A2 | Pyrimidinedione, pyrimidinetrione, triazinedione, tetrahydroquinazolinedione derivatives as alpha-1-adrenergic receptor antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-18 | — | — | EP | disclosed |