Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643580 | 0.84 | SLC9A1 (0.58) | SLC9A1KDM4EALDH1A1KAT2BSMN1; SMN2 | |
| SCHEMBL6926451 | 0.83 | SLC9A1 (0.52) | SLC9A1KDM4EALDH1A1POLB | |
| SCHEMBL15110502 | 0.77 | SLC9A1 (0.51) | SLC9A1SMN1; SMN2POLBADRA1DADRA1A | |
| SCHEMBL7641949 | 0.74 | SLC9A1 (0.57) | SLC9A1KDM4EALDH1A1KAT2BMEN1 | |
| SCHEMBL7344009 | 0.73 | TSHR (0.46) | KDM4EALDH1A1KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL2153695 | 0.72 | SLC9A1 (0.63) | SLC9A1KDM4EMEN1KMT2A | |
| SCHEMBL7643597 | 0.72 | SLC9A1 (0.63) | SLC9A1KDM4EALDH1A1ADRA1DADRA1A | |
| SCHEMBL16581427 | 0.72 | ADORA2A (0.48) | SLC9A1SMN1; SMN2POLBADRA1DADRA1A | |
| SCHEMBL28645646 | 0.72 | CHEK1 (0.38) | KDM4EALDH1A1KAT2BSMN1; SMN2PRKACA | |
| SCHEMBL3792986 | 0.71 | SLC9A1 (0.47) | SLC9A1ADRA1DADRA1AADRA1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960121-A4 | PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY | BUCHARDT DORTE (DK) | 2003-05-28 | — | — | EP | disclosed |
| EP-0960121-A1 | PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY | BUCHARDT, Dorte (DK) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998003542-A1 | PEPTIDE NUCLEIC ACIDS HAVING ENHANCED BINDING AFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY | BUCHARDT, DORTE (DK) | 1998-01-29 | — | — | WO | disclosed |
| EP-0586618-A1 | THE USE OF NUCLEIC ACID ANALOGUES IN DIAGNOSTICS AND ANALYTICAL PROCEDURES. | BUCHARDT OLE (DK) | 1994-03-16 | — | — | EP | disclosed |
| EP-0586474-A1 | PEPTIDE NUCLEIC ACIDS | BUCHARDT, Ole (DK) | 1994-03-16 | — | — | EP | disclosed |