SCHEMBL6926574

SCHEMBL6926574

C=CC(=O)NN(CCSSCCN)NC(=O)C=C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
THPO P40225 1/20 0.34
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
EHMT2 Q96KQ7 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11235200 0.80 TSHR (0.42) TSHRTHPOMAPTTDP1EHMT2
SCHEMBL107282 0.73 TSHR (0.39) TSHRTHPOMAPTTDP1EHMT2
SCHEMBL2132212 0.73 TSHR (0.45) TSHRTHPOMAPTTDP1EHMT2
SCHEMBL15377006 0.71 TSHR (0.33) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL26133478 0.71 TSHR (0.50) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL21590125 0.71 TSHR (0.55) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL31707345 0.71 TSHR (0.50) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL1700588 0.71 TSHR (0.55) TSHRTHPOMAPTTDP1EHMT2
SCHEMBL29037561 0.70 TSHR (0.36) TSHRTHPOMAPTTDP1EHMT2
SCHEMBL3319884 0.70 ZDHHC20 (0.42) TSHRTDP1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119818456-A Preparation method of negatively charged melittin nanocapsules targeting tumor microenvironment 北京化工大学 2025-04-15 CN disclosed
CN-116098868-B Size-variable targeted drug-loaded micelle for treating cerebral arterial thrombosis and preparation method thereof 西南交通大学 2024-09-06 CN disclosed
CN-116098868-A Size-variable targeted drug-loaded micelle for treating cerebral arterial thrombosis and preparation method thereof 西南交通大学 2023-05-12 CN disclosed
US-6514535-B2 For drug delivery NOVEON IP HOLDINGS CORP. 2003-02-04 US disclosed
US-20020068087-A1 BIOADHESIVE HYDROGELS WITH FUNCTIONALIZED DEGRADABLE CROSSLINKS NOVEON IP HOLDINGS CORP., FORMERLY KNOWN AS PMD HOLDINGS CORP. 2002-06-06 US disclosed
EP-1178848-A1 BIOADHESIVE HYDROGELS WITH FUNCTIONALIZED DEGRADABLE CROSSLINKS Noveon IP Holdings Corp. (US) 2002-02-13 EP disclosed
WO-2000071180-A1 BIOADHESIVE HYDROGELS WITH FUNCTIONALIZED DEGRADABLE CROSSLINKS NOVEON IP HOLDINGS CORP. (US) 2000-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068087-A1 BIOADHESIVE HYDROGELS WITH FUNCTIONALIZED DEGRADABLE CROSSLINKS CD44, EPCAM, BSG TSHR 1788/4885THPO 3504/4885MAPT 3742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.