Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927334 | 0.97 | METAP2 (0.44) | METAP2CA12CA1CA2CA9 | |
| SCHEMBL6926733 | 0.93 | CA12 (0.45) | METAP2CA12CA1CA2CA9 | |
| SCHEMBL6924834 | 0.93 | CA12 (0.45) | METAP2CA12CA1CA2CA9 | |
| SCHEMBL8126220 | 0.87 | METAP2 (0.36) | METAP2CA12CA1CA2CA9 | |
| SCHEMBL6760613 | 0.85 | ADRB2 (0.41) | CA12CA1CA2CA9ADRB2 | |
| SCHEMBL6760543 | 0.82 | LTB4R (0.42) | CA12CA1CA2CA9ADRB2 | |
| SCHEMBL6760621 | 0.80 | LTB4R (0.43) | CA12CA1CA2CA9ADRB2 | |
| SCHEMBL6760108 | 0.79 | LTB4R (0.45) | CA12CA1CA2CA9ADRB2 | |
| SCHEMBL6762189 | 0.79 | LTB4R (0.45) | CA12CA1CA2CA9ADRB2 | |
| SCHEMBL16572306 | 0.75 | CA1 (0.48) | METAP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099810-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |