Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653807 | 0.84 | LTA4H (0.58) | ALDH1A1TP53LTA4HUSP2CYP1A2 | |
| SCHEMBL6324652 | 0.80 | HPGD (0.63) | NPSR1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL21774158 | 0.78 | LMNA (0.47) | NPSR1MAPTL3MBTL1HPGDTSHR | |
| SCHEMBL3734067 | 0.76 | ALDH1A1 (0.58) | NPSR1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL7061698 | 0.75 | LMNA (0.63) | NPSR1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL22362132 | 0.72 | KMT2A (0.59) | MAPTALDH1A1HPGDLTA4HSMN1; SMN2 | |
| SCHEMBL3731329 | 0.71 | ALDH1A1 (0.57) | NPSR1MAPTL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL5847214 | 0.71 | KMT2A (0.58) | MAPTALDH1A1HPGDLTA4HSMN1; SMN2 | |
| SCHEMBL766897 | 0.70 | MAPT (0.58) | MAPTALDH1A1HPGDLTA4HSMN1; SMN2 | |
| SCHEMBL25786343 | 0.70 | MAPT (0.57) | NPSR1MAPTL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514975-B1 | Tetrazoles as selective agonists for the delta opioid receptor | PFIZER INC | 2003-02-04 | — | — | US | disclosed |