SCHEMBL6926735

SCHEMBL6926735

CC(C)c1cn(C2CCN(C)CC2)c2ncnc(N)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 11/20 0.50
ABL1 P00519 8/20 0.48
EGFR P00533 8/20 0.48
LCK P06239 5/20 0.48
FYN P06241 3/20 0.48
KDR P35968 3/20 0.48
RET P07949 3/20 0.48
BTK Q06187 3/20 0.48
HCK P08631 3/20 0.48
TEK Q02763 3/20 0.48
MAP4K4 O95819 2/20 0.48
PAK4 O96013 2/20 0.48
CSF1R P07333 2/20 0.48
FGFR1 P11362 2/20 0.48
FLT1 P17948 2/20 0.48
FLT3 P36888 2/20 0.48
CSNK1A1 P48729 2/20 0.48
LIMK1 P53667 2/20 0.48
MAP4K2 Q12851 2/20 0.48
ROCK1 Q13464 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10198690 0.88 SRC (0.47) SRCABL1EGFRLCKFYN
SCHEMBL6927089 0.85 SRC (0.55) SRCABL1EGFRLCKFYN
SCHEMBL14644244 0.83 RIPK2 (0.52) SRCABL1EGFRLCKFYN
SCHEMBL6925160 0.82 RET (0.52) SRCABL1EGFRLCKFYN
SCHEMBL17085734 0.82 ADK (0.51) SRCABL1EGFRLCKFYN
SCHEMBL19743546 0.82 MTOR (0.52) SRCABL1EGFRLCKFYN
SCHEMBL6926802 0.82 SRC (0.51) SRCABL1EGFRLCKFYN
SCHEMBL8320799 0.79 SRC (0.81) SRCABL1EGFRLCKFYN
SCHEMBL20351777 0.77 SRC (0.66) SRCABL1EGFRLCKFYN
SCHEMBL24251908 0.75 ADK (0.48) SRCABL1EGFRLCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116779-A1 DIALKYNE COMPOUND AND USE THEREOF 上海艾力斯医药科技股份有限公司 2023-06-29 WO disclosed
US-20130018038-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC 2013-01-17 US disclosed
WO-2011119663-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC (US) 2011-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130018038-A1 CHEMICAL COMPOUNDS BRCA1, IRS1, IGF1R SRC 2497/4885ABL1 1021/4885EGFR 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.