Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.81 |
| ▸ | EGFR | P00533 | 13/20 | 0.78 |
| ▸ | ABL1 | P00519 | 10/20 | 0.78 |
| ▸ | ABL2 | P42684 | 9/20 | 0.78 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.74 |
| ▸ | LCK | P06239 | 6/20 | 0.70 |
| ▸ | TEK | Q02763 | 5/20 | 0.70 |
| ▸ | KDR | P35968 | 3/20 | 0.70 |
| ▸ | FYN | P06241 | 2/20 | 0.70 |
| ▸ | LYN | P07948 | 2/20 | 0.70 |
| ▸ | CSK | P41240 | 2/20 | 0.70 |
| ▸ | BTK | Q06187 | 2/20 | 0.70 |
| ▸ | HCK | P08631 | 2/20 | 0.70 |
| ▸ | PLK4 | O00444 | 1/20 | 0.70 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.70 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.70 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.70 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.70 |
| ▸ | PAK4 | O96013 | 1/20 | 0.70 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20351777 | 0.91 | SRC (0.66) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL132510 | 0.88 | SRC (1.00) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL6465399 | 0.87 | LCK (0.89) | SRCEGFRABL1LCKTEK | |
| SCHEMBL5936173 | 0.86 | SRC (0.97) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL8320765 | 0.86 | SRC (0.75) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL20351637 | 0.86 | SRC (0.65) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL7020164 | 0.86 | SRC (0.81) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL8114235 | 0.85 | SRC (0.71) | SRCEGFRABL1ABL2RIPK2 | |
| Hydrochloric Acid SCHEMBL7098308 | 0.83 | SRC (0.85) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL23847631 | 0.83 | SRC (0.77) | SRCEGFRABL1ABL2RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888353-A1 | NOVEL N-7-HETEROCYCLYL PYRROLO 2,3-D]PYRIDINES AND THEIR USE | Novartis AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034895-A1 | NOVEL N-7-HETEROCYCLYL PYRROLO[2,3-D]PYRIDINES AND THEIR USE | NOVARTIS AG (CH) | 1997-09-25 | — | — | WO | disclosed |