Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 10/20 | 0.45 |
| ▸ | ABL1 | P00519 | 7/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | PAK4 | O96013 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | RET | P07949 | 2/20 | 0.45 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651203 | 0.92 | ABL1 (0.49) | ADKRIPK2SRCABL1FGFR1 | |
| SCHEMBL14644244 | 0.92 | RIPK2 (0.52) | ADKRIPK2SRCABL1FGFR1 | |
| SCHEMBL14643787 | 0.89 | ADK (0.52) | ADKRIPK2SRCABL1FGFR1 | |
| SCHEMBL16236916 | 0.86 | MTOR (0.50) | ADKRIPK2SRCABL1FGFR1 | |
| SCHEMBL24072104 | 0.84 | RIPK2 (0.61) | ADKRIPK2SRCABL1FGFR1 | |
| SCHEMBL19264162 | 0.82 | SRC (0.61) | ADKRIPK2SRCABL1FGFR1 | |
| SCHEMBL13020153 | 0.79 | SRC (0.58) | RIPK2SRCABL1FGFR1MAP4K4 | |
| SCHEMBL16236082 | 0.79 | ABL1 (0.48) | ADKSRCABL1FGFR1MAP4K4 | |
| SCHEMBL30120727 | 0.79 | ABL1 (0.48) | ADKSRCABL1FGFR1MAP4K4 | |
| SCHEMBL10261381 | 0.78 | FGR (0.57) | ADKRIPK2SRCABL1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033532-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |