Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylacetylene SCHEMBL27943421 | 0.94 | TSHR (0.76) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL404435 | 0.93 | TSHR (0.62) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL69268 | 0.92 | PTPN11 (0.69) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL23128710 | 0.87 | PTPN11 (0.56) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL1535874 | 0.86 | PTPN11 (0.63) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL19168005 | 0.86 | POLB (0.53) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL19168576 | 0.86 | POLB (0.53) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL2747144 | 0.85 | TSHR (0.57) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL5685399 | 0.85 | TSHR (0.57) | TSHRPTPN11MAPTRAB9AL3MBTL1 | |
| SCHEMBL16140276 | 0.85 | TDP1 (0.77) | TSHRPTPN11MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274886-A1 | Crosslinkable Soluble Aromatic Polyester | TICONA LLC | 2015-10-01 | — | — | US | claimed |
| US-9145519-B2 | Crosslinkable aromatic polyester | TICONA LLC (US) | 2015-09-29 | — | — | US | claimed |
| WO-2014047015-A1 | CROSSLINKABLE AROMATIC POLYESTER | TICONA LLC (US) | 2014-03-27 | — | — | WO | claimed |
| US-20140088247-A1 | Crosslinkable Aromatic Polyester | TICONA LLC (US) | 2014-03-27 | — | — | US | claimed |
| US-12435051-B2 | Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof | VIVOZON, INC. (KR) | 2025-10-07 | — | — | US | disclosed |
| US-20240360092-A1 | DUAL MODULATOR OF MGLUR5 AND 5-HT2A RECEPTOR, AND USE THEREOF | VIVOZON INC. (KR) | 2024-10-31 | — | — | US | disclosed |
| US-12060339-B2 | Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof | VIVOZON INC. (KR) | 2024-08-13 | — | — | US | disclosed |
| EP-4190770-A1 | DUAL REGULATOR FOR MGLUR5 AND 5-HT2A RECEPTORS AND USE THEREOF | Vivozon, Inc. (KR) | 2023-06-07 | — | — | EP | disclosed |
| EP-4190770-A1 | DUAL REGULATOR FOR MGLUR5 AND 5-HT2A RECEPTORS AND USE THEREOF | Vivozon, Inc. (KR) | 2023-06-07 | — | — | EP | disclosed |
| CN-116234552-A | Dual modulators of mGluR5 and 5-HT2A receptors and uses thereof | (株)倍宝尊 | 2023-06-06 | — | — | CN | disclosed |
| US-20220274939-A1 | DUAL MODULATOR OF MGLUR5 AND 5-HT2A RECEPTOR, AND USE THEREOF | VIVOZON INC. (KR) | 2022-09-01 | — | — | US | disclosed |
| US-11383220-B1 | Method and material for synthesis and purification by use of a coated solid substrate | Faster Chemistry LLC (US) | 2022-07-12 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20090287016-A1 | Transition-Metal-Catalyzed Carbon-Nitrogen and Carbon-Carbon Bond-Forming Reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-11-19 | — | — | US | disclosed |
| US-7560596-B2 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080226618-A1 | HYDANTOIN DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | SCHERING CORPORATION | 2008-09-18 | — | — | US | disclosed |
| US-20070043234-A1 | Use of functionalized onium salts as a soluble support for organic synthesis | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-02-22 | — | — | US | disclosed |
| US-20060173186-A1 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-08-03 | — | — | US | disclosed |
| US-3935239-A | Process for producing aromatic α-diketones | NEILAND OYAR YANOVICH | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090287016-A1 | Transition-Metal-Catalyzed Carbon-Nitrogen and Carbon-Carbon Bond-Forming Reactions | NBAS, APEX1, CBR3 | TSHR 2373/4885PTPN11 4007/4885MAPT 3263/4885 |
| US-12435051-B2 | Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof | GRM5, HTR5A, HTR2A | TSHR 611/4885PTPN11 1145/4885MAPT 3933/4885 |
| US-20060173186-A1 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | NBAS, APEX1, CBR3 | TSHR 2373/4885PTPN11 4007/4885MAPT 3263/4885 |
| US-20240360092-A1 | DUAL MODULATOR OF MGLUR5 AND 5-HT2A RECEPTOR, AND USE THEREOF | GRM5, HTR5A, HTR2A | TSHR 611/4885PTPN11 1145/4885MAPT 3933/4885 |
| US-20080226618-A1 | HYDANTOIN DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | LPXN, HAX1, LCT | TSHR 4380/4885PTPN11 4252/4885MAPT 3987/4885 |
| US-20070043234-A1 | Use of functionalized onium salts as a soluble support for organic synthesis | NOS1, NOS2, F12 | TSHR 3095/4885PTPN11 1900/4885MAPT 862/4885 |
| US-12060339-B2 | Dual modulator of mGluR5 and 5-HT2A receptor, and use thereof | GRM5, HTR5A, HTR2A | TSHR 611/4885PTPN11 1145/4885MAPT 3933/4885 |
| US-20220274939-A1 | DUAL MODULATOR OF MGLUR5 AND 5-HT2A RECEPTOR, AND USE THEREOF | GRM5, HTR5A, HTR2A | TSHR 611/4885PTPN11 1145/4885MAPT 3933/4885 |
| US-20100324025-A1 | Antibacterial Agents | MRPL21, SI, PGLS | TSHR 4122/4885PTPN11 3357/4885MAPT 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.