Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 9/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | FSHR | P23945 | 2/20 | 0.56 |
| ▸ | BRAF | P15056 | 4/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331233 | 0.90 | LHCGR (0.77) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL6928354 | 0.87 | LHCGR (0.58) | LHCGRTSHRFSHRBRAFCHRM4 | |
| SCHEMBL4421168 | 0.86 | LHCGR (0.84) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4421145 | 0.86 | BRAF (0.62) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL5025967 | 0.86 | LHCGR (0.62) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4431522 | 0.84 | LHCGR (0.62) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL6217958 | 0.81 | CHRM4 (0.60) | LHCGRTSHRFSHRCHRM4HPGD | |
| SCHEMBL4325451 | 0.81 | LHCGR (0.75) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4322522 | 0.80 | LHCGR (0.81) | LHCGRTSHRFSHRBRAFPDE4A | |
| SCHEMBL4331127 | 0.80 | LHCGR (0.76) | LHCGRTSHRFSHRBRAFPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569863-B1 | Luteinizing hormone (LH) agonists for controlling fertility | AKZO NOBEL NV (NL) | 2003-05-27 | — | — | US | disclosed |