Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463889 | 0.88 | CTSL (0.49) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL7464557 | 0.83 | GRN (0.52) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL6927425 | 0.83 | CTSL (0.55) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL7464820 | 0.82 | CTSL (0.47) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL7467469 | 0.81 | CTSL (0.47) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL6927525 | 0.81 | CTSL (0.49) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL7467318 | 0.81 | CTSL (0.53) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL7609373 | 0.80 | HSPA5 (0.49) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL7462272 | 0.80 | CTSL (0.50) | CTSLCTSBCTSSCTSKCNR2 | |
| SCHEMBL7462346 | 0.80 | CTSK (0.47) | CTSLCTSBCTSSCTSKCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |