Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.55 |
| ▸ | CTSB | P07858 | 8/20 | 0.55 |
| ▸ | CTSS | P25774 | 8/20 | 0.55 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSV | O60911 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473777 | 0.92 | CTSL (0.53) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7462272 | 0.92 | CTSL (0.50) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6927525 | 0.91 | CTSL (0.49) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7473976 | 0.91 | CTSL (0.49) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7467318 | 0.91 | CTSL (0.53) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7463889 | 0.90 | CTSL (0.49) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7462366 | 0.90 | CTSS (0.53) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7467469 | 0.90 | CTSL (0.47) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7473345 | 0.90 | TAS1R3 (0.54) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL7466927 | 0.90 | CTSL (0.48) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |