Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 1.00 |
| ▸ | NR1H2 | P55055 | 1/20 | 1.00 |
| ▸ | NR1H3 | Q13133 | 1/20 | 1.00 |
| ▸ | ANPEP | P15144 | 5/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820118 | 0.88 | DPP4 (0.78) | DPP4NR1H2NR1H3ANPEPFAAH | |
| SCHEMBL29366407 | 0.88 | DPP4 (0.78) | DPP4NR1H2NR1H3ANPEPFAAH | |
| SCHEMBL6923966 | 0.88 | DPP4 (0.78) | DPP4NR1H2NR1H3ANPEPFAAH | |
| SCHEMBL10718972 | 0.80 | DPP4 (0.65) | DPP4NR1H2NR1H3ANPEPKMT2A | |
| SCHEMBL29379602 | 0.79 | DPP4 (0.65) | DPP4NR1H2NR1H3ANPEPKMT2A | |
| SCHEMBL9612014 | 0.78 | DPP4 (0.63) | DPP4NR1H2NR1H3ANPEPFAAH | |
| SCHEMBL29382416 | 0.76 | DPP4 (0.61) | DPP4NR1H2NR1H3ANPEPFAAH | |
| SCHEMBL17531021 | 0.76 | ANPEP (0.67) | DPP4NR1H2NR1H3ANPEPFAAH | |
| SCHEMBL30954668 | 0.76 | ANPEP (0.67) | DPP4NR1H2NR1H3ANPEPFAAH | |
| SCHEMBL300362 | 0.75 | DPP4 (0.61) | DPP4NR1H2NR1H3ANPEPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3404059-B1 | METHOD FOR MANUFACTURING SURFACE-MODIFIED THERMOPLASTIC RESIN | NITTO DENKO CORP (JP) | 2023-03-01 | — | — | EP | disclosed |
| CN-115284695-A | Bonded structure, thermal transfer surface-modified sheet, thermoplastic resin with modified sheet, and surface-modified thermoplastic resin | 日东电工株式会社 | 2022-11-04 | — | — | CN | disclosed |
| US-6515129-B1 | A pharmaceutical composition which comprises, a cyclic imide derivative represented by the general formula (I): present invention relates to an aminopeptidase N inhibitor or an angiogenesis inhibitor, modulates production of tumor necrosis | ISHIHARA SANGYO KAISHA LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6429212-B1 | AMINOPEPTIDASE N INHIBITOR USED TO TREAT CANCER, TUMORS, AND RETINOPATHY; FEW SIDE EFFECTS; ANGIOGENESIS INHIBITOR | ISHIHARA SANGYO KAISHA LTD. (JP) | 2002-08-06 | — | — | US | disclosed |