Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927085 | 0.76 | PRKCZ (0.41) | PRKCZMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6927654 | 0.74 | PRKCZ (0.66) | PRKCZMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6925740 | 0.74 | PRKCZ (0.40) | PRKCZMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27470127 | 0.73 | USP2 (0.54) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6925779 | 0.73 | NPC1 (0.38) | PRKCZMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27815444 | 0.73 | PRKCZ (0.47) | PRKCZMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4259769 | 0.73 | PRKCZ (0.56) | PRKCZMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2369108 | 0.72 | PRKCZ (0.63) | PRKCZMAPTALDH1A1TSHRMAPK1 | |
| SCHEMBL6929041 | 0.72 | PRKCZ (0.56) | PRKCZMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL690269 | 0.71 | PRKCZ (1.00) | PRKCZMAPTALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |