Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927085 | 0.82 | PRKCZ (0.41) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL6927702 | 0.74 | PRKCZ (0.43) | MAPTPRKCZ | |
| SCHEMBL6925740 | 0.73 | PRKCZ (0.40) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL6927294 | 0.73 | PRKCZ (0.54) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL15674527 | 0.64 | — | — | |
| SCHEMBL1167821 | 0.63 | — | — | |
| SCHEMBL6926287 | 0.63 | POLB (0.36) | MAPTPRKCZ | |
| SCHEMBL23205871 | 0.61 | CD44 (0.36) | MAPT | |
| SCHEMBL13614897 | 0.61 | PTPRC (0.47) | NPC1MAPTALOX5APFEN1 | |
| SCHEMBL13446768 | 0.61 | FEN1 (0.40) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |