Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941182 | 0.85 | RAB9A (0.66) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL6929101 | 0.84 | NPC1 (0.44) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL2806065 | 0.83 | NPC1 (0.59) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL3297579 | 0.83 | NPC1 (0.81) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL564179 | 0.80 | RAB9A (0.61) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL29814623 | 0.80 | RAB9A (0.61) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL9408806 | 0.80 | NPC1 (0.66) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL10714551 | 0.80 | NPC1 (0.58) | NPC1RAB9ALMNAKDM4EMAPT | |
| SCHEMBL6930005 | 0.79 | NPC1 (0.54) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL6930002 | 0.78 | NPC1 (0.50) | NPC1RAB9ALMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756499-B2 | REACTING A BROMO-FUNCTIONALIZED BENZOTRIAZOLE ULTRAVIOLET RADIATION(UV) ABSORBER | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-06-29 | — | — | US | disclosed |
| US-20020082428-A1 | Process for the preparation of novel diol-functionalized UV absorbers | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2002-06-27 | — | — | US | disclosed |
| US-6320056-B1 | REACTING A 2-(2-HYDROXY-5-MEHTYLPHENYL)BENZOTIAZOLE WITH BROMINE IN PRESENCE OF NON-POLAR SOLVENT AND FREE RADICAL INITIATOR, SEPARATING SOLVENT AND PURIFYING BY RECRYSTALLIZATION; ONE STEP | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2001-11-20 | — | — | US | disclosed |
| US-6307055-B1 | OPTIONALLY SUBSTITUTED 2-(2-HYDROXY-5-(N,N-BIS(HYDROXYALKYL)AMINOMETHYL)PHENYL)BENZOT RIAZOLES; UV ABSORBERS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2001-10-23 | — | — | US | disclosed |
| US-6284895-B1 | Bromo-functionalized benzotriazole UV absorbers | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2001-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082428-A1 | Process for the preparation of novel diol-functionalized UV absorbers | UGT1A1, ERCC1, CYP1B1 | NPC1 432/4885RAB9A 1317/4885LMNA 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.