SCHEMBL2806065

SCHEMBL2806065

CCOc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.59
RAB9A P51151 5/20 0.59
LMNA P02545 1/20 0.59
KDM4E B2RXH2 3/20 0.52
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
PKM P14618 1/20 0.45
MAPT P10636 2/20 0.42
RXFP1 Q9HBX9 1/20 0.42
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
POLB P06746 1/20 0.40
MPO P05164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10620345 0.89 LMNA (0.56) NPC1RAB9ALMNAKDM4EKMT2A
SCHEMBL9408814 0.89 NPC1 (0.56) NPC1RAB9ALMNAKDM4EMEN1
SCHEMBL29768249 0.89 NPC1 (0.56) NPC1RAB9ALMNAKDM4EMEN1
SCHEMBL29510512 0.88 KDM4E (0.52) NPC1RAB9ALMNAKDM4EMEN1
SCHEMBL16412543 0.88 KDM4E (0.52) NPC1RAB9ALMNAKDM4EMEN1
SCHEMBL831880 0.85 NPC1 (0.52) NPC1RAB9ALMNAKDM4E
SCHEMBL11135110 0.84 NPC1 (0.54) NPC1RAB9ALMNAKDM4EMAPT
SCHEMBL544710 0.83 LMNA (0.54) NPC1RAB9ALMNAKDM4EMEN1
SCHEMBL6927326 0.83 NPC1 (0.61) NPC1RAB9ALMNAKDM4EMEN1
SCHEMBL29768260 0.83 RAB9A (0.64) NPC1RAB9ALMNAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100239792-A1 THERMAL PRINTING LAYER AND OPTICAL RECORDING MEDIUM USING THE THERMAL PRINTING LAYER MITSUBISHI KAGAKU MEDIA CORPORATION, LTD. (JP) 2010-09-23 US disclosed
EP-2011662-B1 OPTICAL RECORDING MEDIUM WITH A HEAT-SENSITIVE PRINTING LAYER MITSUBISHI KAGAKU MEDIA CO LTD (JP) 2010-07-07 EP disclosed
US-20090209421-A1 THERMAL PRINTING LAYER AND OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2009-08-20 US disclosed
EP-2011662-A1 HEAT-SENSITIVE PRINTING LAYER AND OPTICAL RECORDING MEDIUM Mitsubishi Kagaku Media Co., Ltd. (JP) 2009-01-07 EP disclosed
EP-2011663-A1 HEAT-SENSITIVE PRINTING LAYER AND OPTICAL RECORDING MEDIUM USING THE HEAT-SENSITIVE PRINTING LAYER Mitsubishi Kagaku Media Co., Ltd. (JP) 2009-01-07 EP disclosed
EP-1016547-B1 Method and material for erasable recording by heat RICOH KK (JP) 2006-03-29 EP disclosed
EP-1587091-A1 INFORMATION RECORDING MEDIUM Mitsubishi Chemical Corporation (JP) 2005-10-19 EP disclosed
WO-2005094777-A1 EXTERNAL PREPARATION FOR SKIN SHOWA DENKO K.K. (JP) 2005-10-13 WO disclosed
US-20050130840-A1 INFORMATION RECORDING-DISPLAYING CARD, IMAGE PROCESSING METHOD USING SAME, AND IMAGE PROCESSOR MITSUBISHI PLASTICS, INC. (JP) 2005-06-16 US disclosed
US-20050036768-A1 Information recording medium MITSUBISHI CHEMICAL CORPORATION (JP) 2005-02-17 US disclosed
US-5739077-A FOR BLOCK COPY FILM FOR PLATE-MAKING IN GRAVURE PRINTING RICOH COMPANY, LTD. (JP) 1998-04-14 US disclosed
US-5712221-A Thermal recording medium RICOH COMPANY, LTD. (JP) 1998-01-27 US disclosed
US-5583088-A ELECTRON DONOR, ELECTRON ACCEPTOR, DECOLORIZATION PROMOTER AGENT, BINDER RESIN RICOH COMPANY, LTD. (JP) 1996-12-10 US disclosed
EP-0492628-B1 Reversible thermosensitive coloring composition, recording medium, recording method and image display apparatus using the recording medium RICOH KK (JP) 1996-07-03 EP disclosed
EP-0688680-A1 Transparent thermal recording medium Ricoh Company, Ltd (JP) 1995-12-27 EP disclosed
US-5432534-A Reversible thermosensitive coloring composition, recording medium, recording method, and image display apparatus using the recording medium RICOH COMPANY, LTD. (JP) 1995-07-11 US disclosed
US-5395433-A Containing electron donor coloring and electron acceptor compounds which react to induce color formation; printers for computers, facsimile apparatus RICOH COMPANY, LTD. (JP) 1995-03-07 US disclosed
US-5380693-A Protective layer RICOH COMPANY, LTD. (JP) 1995-01-10 US disclosed
US-5296439-A Support with reversible thermosensitive coloring recording layer containing electron donor coloring compound, electron acceptor which reacts to induce color formation RICOH COMPANY, LTD. (JP) 1994-03-22 US disclosed
EP-0492628-A1 Reversible thermosensitive coloring composition, recording medium, recording method and image display apparatus using the recording medium Ricoh Company, Ltd (JP) 1992-07-01 EP disclosed