Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928192 | 0.87 | HTR4 (0.42) | HTR4NPY1RSLC6A4MERTKACP1 | |
| SCHEMBL6928365 | 0.82 | AVPR2 (0.39) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL6925839 | 0.82 | HTR4 (0.39) | KDM4EALDH1A1SMN1; SMN2HSD17B10HTR4 | |
| SCHEMBL6924876 | 0.82 | HTR4 (0.39) | HTR4NPY1RSLC6A4MERTKACP1 | |
| SCHEMBL6927485 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL6929021 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL6927038 | 0.81 | ACP1 (0.38) | HTR4NPY1RMERTKACP1HTR6 | |
| SCHEMBL6929821 | 0.81 | HTR4 (0.40) | HTR4NPY1RSLC6A4MERTKACP1 | |
| SCHEMBL6923656 | 0.81 | HTR4 (0.38) | KDM4EALDH1A1TSHRHSD17B10HTR4 | |
| SCHEMBL6924606 | 0.80 | HTR4 (0.39) | HTR4NPY1RSLC6A4MERTKACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |