Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 6/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 5/20 | 0.37 |
| ▸ | CASP7 | P55210 | 5/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928340 | 0.90 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CASRTSHRLMNA | |
| SCHEMBL6838677 | 0.88 | CASR (0.40) | ALDH1A1SMN1; SMN2CASRTSHRLMNA | |
| SCHEMBL6928192 | 0.86 | HTR4 (0.42) | HTR4NPY1R | |
| SCHEMBL6838688 | 0.85 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2CASRTSHRLMNA | |
| SCHEMBL6924876 | 0.82 | HTR4 (0.39) | HTR4NPY1R | |
| SCHEMBL6928365 | 0.82 | AVPR2 (0.39) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL6927438 | 0.82 | KDM4E (0.40) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL6925839 | 0.82 | HTR4 (0.39) | ALDH1A1SMN1; SMN2HSD17B10KDM4EHPGD | |
| SCHEMBL6929021 | 0.81 | KDM4E (0.40) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| SCHEMBL6927038 | 0.80 | ACP1 (0.38) | HTR4POLBNPY1RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |