Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5587976 | 0.79 | DPP4 (0.35) | ALDH1A1THRBKDM4EHPGDHSD17B10 | |
| SCHEMBL27977844 | 0.79 | ALDH1A1 (0.42) | ALDH1A1THRBKDM4EHPGDHSD17B10 | |
| SCHEMBL24488780 | 0.78 | ALDH1A1 (0.39) | ALDH1A1THRBHPGDHSD17B10LMNA | |
| SCHEMBL27303224 | 0.75 | HTT (0.44) | ALDH1A1THRBKDM4EHPGDHSD17B10 | |
| SCHEMBL29065578 | 0.72 | THRB (0.41) | ALDH1A1THRBKDM4EHPGDHSD17B10 | |
| SCHEMBL22490898 | 0.71 | PDE4D (0.45) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL5588041 | 0.71 | THRB (0.37) | ALDH1A1THRBKDM4EHPGDHSD17B10 | |
| SCHEMBL14736337 | 0.71 | TSHR (0.41) | ALDH1A1THRBKDM4EHPGDHSD17B10 | |
| SCHEMBL29836145 | 0.71 | TSHR (0.41) | ALDH1A1THRBKDM4EHPGDHSD17B10 | |
| SCHEMBL6928988 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363924-A1 | AVILAMYCIN DERIVATIVES | Combinature Biopharm AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002068436-A1 | AVILAMYCIN DERIVATIVES | COMBINATURE BIOPHARM AG (DE) | 2002-09-06 | — | — | WO | disclosed |